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Entry title:

Antimicrobial resistance in Streptococcus pneumoniae (S. pneumoniae) bacteraemia

Last updated on Thursday, 29 January 2026 at 04:00pm

This page provides information on resistance to antimicrobials in Streptococcus pneumoniae bacteraemia (bacteria found in blood specimens). Data breakdowns are available for England and by UKHSA Region.

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Overview

Antibiotics are grouped based on the UK-AWaRe classification. These are:

Access
Access antibiotics are with a narrow spectrum of activity, fewer side effects, lower costs, and importantly lower resistance potential. These are first or second choice antibiotics recommended for empiric treatment of the most common infections and should be widely available. That is to say, these antibiotics should offer the best therapeutic value while minimizing the potential for resistance.

Watch
Watch antibiotics have a higher resistance potential and are broader-spectrum antibiotics. These are first or second choice antibiotics indicated for a limited number of infective syndromes. As these antibiotics are considered to have a higher potential for selection of AMR, their use should be carefully monitored.

Reserve
Reserve antibiotics are “last resort” antibiotics, including new antibiotics. These are used for highly selected patients (life-threatening infections due to multi-drug-resistant bacteria) and are closely monitored and prioritized as targets of stewardship programmes to ensure continued effectiveness.

Resistance

Rolling monthly average percent of S. pneumoniae bacteraemia resistant to macrolides and penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere are 2 plots on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is plot number 1 on this chart. This is a dark blue solid line plot. The plot has a label of 'Macrolides (Watch)'. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentResistantRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 7.89 on 01 November 2020 to 5.66 on 01 September 2021. It fell from 7.22 on 01 October 2021 to 5.32 on 01 July 2022. It rose from 6.28 on 01 August 2022 to 7.32 on 01 May 2023. It rose from 6.29 on 01 June 2023 to 7.53 on 01 March 2024. It rose from 7.5 on 01 April 2024 to 8.48 on 01 January 2025. And finally. It rose from 7.7 on 01 February 2025 to 7.78 on 01 November 2025. This is plot number 2 on this chart. This is a turquoise solid line plot. The plot has a label of 'Penicillin (Access)'. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentResistantRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 3.03 on 01 November 2020 to 1.33 on 01 September 2021. It fell from 1.92 on 01 October 2021 to 1.35 on 01 July 2022. It rose from 0.97 on 01 August 2022 to 1.72 on 01 May 2023. It rose from 2.13 on 01 June 2023 to 2.75 on 01 March 2024. It fell from 2.75 on 01 April 2024 to 2.22 on 01 January 2025. And finally. It rose from 2.12 on 01 February 2025 to 3.73 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Resistance data for rolling monthly average percent of S. pneumoniae bacteraemia resistant to macrolides and penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

MonthMacrolides (Watch)Penicillin (Access)
1 Nov 20257.783.73
1 Oct 20259.453.08
1 Sep 202510.202.47
1 Aug 202510.232.88
1 Jul 202510.093.11
1 Jun 20259.113.15
1 May 20258.932.79
1 Apr 20257.542.47
1 Mar 20257.972.22
1 Feb 20257.702.12
1 Jan 20258.482.22
1 Dec 20248.472.10
1 Nov 20248.281.74
1 Oct 20247.711.29
1 Sep 20247.452.44
1 Aug 20248.192.53
1 Jul 20247.603.78
1 Jun 20247.073.77
1 May 20246.893.70
1 Apr 20247.502.75
1 Mar 20247.532.75
1 Feb 20247.262.31
1 Jan 20246.442.10
1 Dec 20236.841.42
1 Nov 20237.411.36
1 Oct 20237.541.19
1 Sep 20236.042.18
1 Aug 20235.032.42
1 Jul 20234.812.36
1 Jun 20236.292.13
1 May 20237.321.72
1 Apr 20237.921.75
1 Mar 20237.591.40
1 Feb 20235.811.43
1 Jan 20235.611.72
1 Dec 20225.442.36
1 Nov 20226.833.13
1 Oct 20226.912.72
1 Sep 20225.610.68
1 Aug 20226.280.97
1 Jul 20225.321.35
1 Jun 20224.591.43
1 May 20223.601.26
1 Apr 20224.441.02
1 Mar 20225.381.20
1 Feb 20226.151.97
1 Jan 20226.271.74
1 Dec 20217.312.26
1 Nov 20217.701.97
1 Oct 20217.221.92
1 Sep 20215.661.33
1 Aug 20216.221.72
1 Jul 20216.222.37
1 Jun 20217.322.38
1 May 20216.612.35
1 Apr 20218.232.58
1 Mar 202110.192.54
1 Feb 202110.203.06
1 Jan 202110.183.00
1 Dec 20207.762.88
1 Nov 20207.893.03
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Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Macrolides

Testing

Rolling monthly average number of S. pneumoniae bacteraemia tested for resistance to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid bar plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaNumberTestedRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It rose from 118.33 on 01 November 2020 to 141.33 on 01 September 2021. It rose from 189.33 on 01 October 2021 to 213.0 on 01 July 2022. It rose from 185.67 on 01 August 2022 to 359.67 on 01 May 2023. It rose from 302.0 on 01 June 2023 to 460.67 on 01 March 2024. It rose from 422.0 on 01 April 2024 to 566.33 on 01 January 2025. And finally. It fell from 580.0 on 01 February 2025 to 295.67 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Testing data for rolling monthly average number of S. pneumoniae bacteraemia tested for resistance to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

MonthNumber tested
1 Nov 2025295.67
1 Oct 2025243.33
1 Sep 2025183.00
1 Aug 2025205.33
1 Jul 2025271.00
1 Jun 2025366.00
1 May 2025425.67
1 Apr 2025451.00
1 Mar 2025485.33
1 Feb 2025580.00
1 Jan 2025566.33
1 Dec 2024495.67
1 Nov 2024310.00
1 Oct 2024229.00
1 Sep 2024183.33
1 Aug 2024215.67
1 Jul 2024276.33
1 Jun 2024325.33
1 May 2024372.33
1 Apr 2024422.00
1 Mar 2024460.67
1 Feb 2024519.00
1 Jan 2024476.00
1 Dec 2023424.00
1 Nov 2023279.00
1 Oct 2023207.67
1 Sep 2023160.00
1 Aug 2023192.33
1 Jul 2023242.67
1 Jun 2023302.00
1 May 2023359.67
1 Apr 2023395.67
1 Mar 2023417.33
1 Feb 2023510.33
1 Jan 2023487.33
1 Dec 2022447.33
1 Nov 2022263.67
1 Oct 2022197.67
1 Sep 2022160.33
1 Aug 2022185.67
1 Jul 2022213.00
1 Jun 2022247.00
1 May 2022250.00
1 Apr 2022240.00
1 Mar 2022204.33
1 Feb 2022238.67
1 Jan 2022271.33
1 Dec 2021305.67
1 Nov 2021238.00
1 Oct 2021189.33
1 Sep 2021141.33
1 Aug 2021150.00
1 Jul 2021155.33
1 Jun 2021150.33
1 May 2021121.00
1 Apr 202181.00
1 Mar 202168.67
1 Feb 202181.67
1 Jan 202195.00
1 Dec 2020111.67
1 Nov 2020118.33
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Testing

Rolling monthly average percent of S. pneumoniae bacteraemia tested for resistance to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid line plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentTestedRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 97.52 on 01 November 2020 to 94.63 on 01 September 2021. It rose from 94.97 on 01 October 2021 to 95.09 on 01 July 2022. It fell from 95.36 on 01 August 2022 to 94.23 on 01 May 2023. It fell from 93.21 on 01 June 2023 to 93.12 on 01 March 2024. It fell from 92.34 on 01 April 2024 to 91.88 on 01 January 2025. And finally. It fell from 91.77 on 01 February 2025 to 89.67 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Testing data for rolling monthly average percent of S. pneumoniae bacteraemia tested for resistance to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

Month% tested
1 Nov 202589.67
1 Oct 202590.67
1 Sep 202591.50
1 Aug 202593.18
1 Jul 202592.49
1 Jun 202592.19
1 May 202591.40
1 Apr 202591.30
1 Mar 202591.68
1 Feb 202591.77
1 Jan 202591.88
1 Dec 202491.50
1 Nov 202491.45
1 Oct 202491.97
1 Sep 202491.50
1 Aug 202491.49
1 Jul 202491.69
1 Jun 202491.55
1 May 202492.31
1 Apr 202492.34
1 Mar 202493.12
1 Feb 202493.35
1 Jan 202492.61
1 Dec 202392.37
1 Nov 202391.48
1 Oct 202392.00
1 Sep 202390.91
1 Aug 202391.43
1 Jul 202392.02
1 Jun 202393.21
1 May 202394.23
1 Apr 202394.27
1 Mar 202394.99
1 Feb 202394.80
1 Jan 202395.12
1 Dec 202294.50
1 Nov 202294.27
1 Oct 202293.81
1 Sep 202294.67
1 Aug 202295.36
1 Jul 202295.09
1 Jun 202294.64
1 May 202293.98
1 Apr 202294.49
1 Mar 202294.01
1 Feb 202295.20
1 Jan 202294.76
1 Dec 202195.02
1 Nov 202195.20
1 Oct 202194.97
1 Sep 202194.63
1 Aug 202193.75
1 Jul 202193.37
1 Jun 202193.75
1 May 202195.28
1 Apr 202196.43
1 Mar 202194.44
1 Feb 202194.19
1 Jan 202195.96
1 Dec 202096.52
1 Nov 202097.52
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Resistance

Rolling monthly average percent of S. pneumoniae bacteraemia resistant to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid line plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentResistantRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 7.89 on 01 November 2020 to 5.66 on 01 September 2021. It fell from 7.22 on 01 October 2021 to 5.32 on 01 July 2022. It rose from 6.28 on 01 August 2022 to 7.32 on 01 May 2023. It rose from 6.29 on 01 June 2023 to 7.53 on 01 March 2024. It rose from 7.5 on 01 April 2024 to 8.48 on 01 January 2025. And finally. It rose from 7.7 on 01 February 2025 to 7.78 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Resistance data for rolling monthly average percent of S. pneumoniae bacteraemia resistant to macrolides. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

Month% resistant
1 Nov 20257.78
1 Oct 20259.45
1 Sep 202510.20
1 Aug 202510.23
1 Jul 202510.09
1 Jun 20259.11
1 May 20258.93
1 Apr 20257.54
1 Mar 20257.97
1 Feb 20257.70
1 Jan 20258.48
1 Dec 20248.47
1 Nov 20248.28
1 Oct 20247.71
1 Sep 20247.45
1 Aug 20248.19
1 Jul 20247.60
1 Jun 20247.07
1 May 20246.89
1 Apr 20247.50
1 Mar 20247.53
1 Feb 20247.26
1 Jan 20246.44
1 Dec 20236.84
1 Nov 20237.41
1 Oct 20237.54
1 Sep 20236.04
1 Aug 20235.03
1 Jul 20234.81
1 Jun 20236.29
1 May 20237.32
1 Apr 20237.92
1 Mar 20237.59
1 Feb 20235.81
1 Jan 20235.61
1 Dec 20225.44
1 Nov 20226.83
1 Oct 20226.91
1 Sep 20225.61
1 Aug 20226.28
1 Jul 20225.32
1 Jun 20224.59
1 May 20223.60
1 Apr 20224.44
1 Mar 20225.38
1 Feb 20226.15
1 Jan 20226.27
1 Dec 20217.31
1 Nov 20217.70
1 Oct 20217.22
1 Sep 20215.66
1 Aug 20216.22
1 Jul 20216.22
1 Jun 20217.32
1 May 20216.61
1 Apr 20218.23
1 Mar 202110.19
1 Feb 202110.20
1 Jan 202110.18
1 Dec 20207.76
1 Nov 20207.89
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Penicillin

Testing

Rolling monthly average number of S. pneumoniae bacteraemia tested for resistance to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid bar plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaNumberTestedRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It rose from 110.0 on 01 November 2020 to 125.67 on 01 September 2021. It rose from 174.0 on 01 October 2021 to 197.0 on 01 July 2022. It rose from 171.0 on 01 August 2022 to 329.67 on 01 May 2023. It rose from 281.33 on 01 June 2023 to 424.67 on 01 March 2024. It rose from 388.33 on 01 April 2024 to 526.33 on 01 January 2025. And finally. It fell from 533.33 on 01 February 2025 to 268.33 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Testing data for rolling monthly average number of S. pneumoniae bacteraemia tested for resistance to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

MonthNumber tested
1 Nov 2025268.33
1 Oct 2025216.33
1 Sep 2025162.00
1 Aug 2025173.67
1 Jul 2025236.00
1 Jun 2025328.00
1 May 2025383.00
1 Apr 2025405.33
1 Mar 2025436.33
1 Feb 2025533.33
1 Jan 2025526.33
1 Dec 2024460.67
1 Nov 2024286.67
1 Oct 2024206.33
1 Sep 2024164.00
1 Aug 2024198.00
1 Jul 2024256.00
1 Jun 2024301.00
1 May 2024342.33
1 Apr 2024388.33
1 Mar 2024424.67
1 Feb 2024476.00
1 Jan 2024445.33
1 Dec 2023398.00
1 Nov 2023269.00
1 Oct 2023196.67
1 Sep 2023152.67
1 Aug 2023179.33
1 Jul 2023226.00
1 Jun 2023281.33
1 May 2023329.67
1 Apr 2023361.33
1 Mar 2023381.67
1 Feb 2023467.33
1 Jan 2023445.67
1 Dec 2022409.67
1 Nov 2022244.67
1 Oct 2022184.00
1 Sep 2022146.33
1 Aug 2022171.00
1 Jul 2022197.00
1 Jun 2022233.67
1 May 2022238.00
1 Apr 2022229.00
1 Mar 2022194.33
1 Feb 2022219.67
1 Jan 2022248.67
1 Dec 2021279.67
1 Nov 2021220.00
1 Oct 2021174.00
1 Sep 2021125.67
1 Aug 2021135.67
1 Jul 2021140.67
1 Jun 2021140.00
1 May 2021113.33
1 Apr 202177.67
1 Mar 202165.67
1 Feb 202176.33
1 Jan 202189.00
1 Dec 2020104.00
1 Nov 2020110.00
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Testing

Rolling monthly average percent of S. pneumoniae bacteraemia tested for resistance to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid line plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentTestedRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 90.91 on 01 November 2020 to 83.89 on 01 September 2021. It rose from 87.44 on 01 October 2021 to 87.95 on 01 July 2022. It fell from 88.14 on 01 August 2022 to 86.35 on 01 May 2023. It fell from 86.73 on 01 June 2023 to 85.83 on 01 March 2024. It rose from 84.9 on 01 April 2024 to 85.39 on 01 January 2025. And finally. It fell from 84.34 on 01 February 2025 to 81.46 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Testing data for rolling monthly average percent of S. pneumoniae bacteraemia tested for resistance to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

Month% tested
1 Nov 202581.46
1 Oct 202580.60
1 Sep 202581.00
1 Aug 202578.64
1 Jul 202580.55
1 Jun 202582.62
1 May 202582.37
1 Apr 202581.98
1 Mar 202582.42
1 Feb 202584.34
1 Jan 202585.39
1 Dec 202485.03
1 Nov 202484.37
1 Oct 202482.73
1 Sep 202482.00
1 Aug 202484.26
1 Jul 202485.05
1 Jun 202484.79
1 May 202484.86
1 Apr 202484.90
1 Mar 202485.83
1 Feb 202485.61
1 Jan 202486.58
1 Dec 202386.71
1 Nov 202388.20
1 Oct 202387.11
1 Sep 202386.36
1 Aug 202385.24
1 Jul 202385.93
1 Jun 202386.73
1 May 202386.35
1 Apr 202386.16
1 Mar 202386.79
1 Feb 202386.80
1 Jan 202386.91
1 Dec 202286.47
1 Nov 202287.46
1 Oct 202287.62
1 Sep 202286.39
1 Aug 202288.14
1 Jul 202287.95
1 Jun 202289.27
1 May 202289.47
1 Apr 202290.16
1 Mar 202289.40
1 Feb 202287.60
1 Jan 202286.71
1 Dec 202186.92
1 Nov 202188.00
1 Oct 202187.44
1 Sep 202183.89
1 Aug 202184.38
1 Jul 202184.34
1 Jun 202187.50
1 May 202188.98
1 Apr 202191.67
1 Mar 202190.28
1 Feb 202188.37
1 Jan 202189.90
1 Dec 202090.43
1 Nov 202090.91
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

Resistance

Rolling monthly average percent of S. pneumoniae bacteraemia resistant to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including month of 1 Nov 2025

ChartThere is only 1 plot on this chart. The horizontal X-axis is labelled 'date'. Whilst the vertical Y-axis is labelled 'metric'. This is a dark blue solid line plot. This plot shows data for S-pneumoniae. Specifically the metric 's-pneumoniae_testing_bacteraemiaPercentResistantRollingMonth' for the England area, along with the age banding of 'all' for the gender group of all. This plot shows data from 01 November 2020 to 01 November 2025. It fell from 3.03 on 01 November 2020 to 1.33 on 01 September 2021. It fell from 1.92 on 01 October 2021 to 1.35 on 01 July 2022. It rose from 0.97 on 01 August 2022 to 1.72 on 01 May 2023. It rose from 2.13 on 01 June 2023 to 2.75 on 01 March 2024. It fell from 2.75 on 01 April 2024 to 2.22 on 01 January 2025. And finally. It rose from 2.12 on 01 February 2025 to 3.73 on 01 November 2025. There is no reporting delay period being tracked for the data on this chart. - Refer to tabular data.
Tabular data

Resistance data for rolling monthly average percent of S. pneumoniae bacteraemia resistant to penicillin. Monthly figures are shown as the first day of each month. For example, the figures for January 2022 are shown as at "1 Jan 2022".

Up to and including 1 November 2025

Month% resistant
1 Nov 20253.73
1 Oct 20253.08
1 Sep 20252.47
1 Aug 20252.88
1 Jul 20253.11
1 Jun 20253.15
1 May 20252.79
1 Apr 20252.47
1 Mar 20252.22
1 Feb 20252.12
1 Jan 20252.22
1 Dec 20242.10
1 Nov 20241.74
1 Oct 20241.29
1 Sep 20242.44
1 Aug 20242.53
1 Jul 20243.78
1 Jun 20243.77
1 May 20243.70
1 Apr 20242.75
1 Mar 20242.75
1 Feb 20242.31
1 Jan 20242.10
1 Dec 20231.42
1 Nov 20231.36
1 Oct 20231.19
1 Sep 20232.18
1 Aug 20232.42
1 Jul 20232.36
1 Jun 20232.13
1 May 20231.72
1 Apr 20231.75
1 Mar 20231.40
1 Feb 20231.43
1 Jan 20231.72
1 Dec 20222.36
1 Nov 20223.13
1 Oct 20222.72
1 Sep 20220.68
1 Aug 20220.97
1 Jul 20221.35
1 Jun 20221.43
1 May 20221.26
1 Apr 20221.02
1 Mar 20221.20
1 Feb 20221.97
1 Jan 20221.74
1 Dec 20212.26
1 Nov 20211.97
1 Oct 20211.92
1 Sep 20211.33
1 Aug 20211.72
1 Jul 20212.37
1 Jun 20212.38
1 May 20212.35
1 Apr 20212.58
1 Mar 20212.54
1 Feb 20213.06
1 Jan 20213.00
1 Dec 20202.88
1 Nov 20203.03
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About

Source: AMR module of Second Generation Surveillance System (SGSS). SGSS is a live reporting database, and therefore data is subject to change. Note 1: The chart shows a three-month rolling average, so the data shown for one month is the average across that month and the previous two months. Note 2: Interpreting national antibiotic resistance surveillance trends spanning European Committee on Antimicrobial Susceptibility Testing (EUCAST) clinical breakpoint transition periods requires additional consideration to avoid misinterpretation of data.

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