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Entry title:
Hepatitis B (HBV)
Last updated on Thursday, 20 November 2025 at 04:00pm
Hepatitis B virus (HBV) is a bloodborne virus (BBV) that infects the liver. Exposure to the hepatitis B virus causes an acute infection, a chronic infection occurs if the virus persists for greater than 6 months and over time can cause severe liver damage leading to cirrhosis, liver failure and cancer. Hepatitis B is vaccine preventable and has been part of the childhood immunisation programme since 2017. Vaccination is also recommended for individuals of all ages at increased risk of exposure to HBV or complications of the disease. These recommendations are outlined in the Green Book.
Through the surveillance of acute and chronic viral hepatitis, UKHSA monitors disease trends, identify populations disproportionately affected and inequities in access and outcomes of care. Data reported by local (NHS or private) or reference laboratories on testing for viral hepatitis is the primary source of surveillance data.
In 2016, the UK signed up to the WHO global health sector strategy (GHSS) to eliminate viral hepatitis as a public health threat by 2030. To validate elimination of viral hepatitis, it is necessary to demonstrate the achievement of the WHO impact and programmatic targets. The impact targets include absolute thresholds for incidence and mortality, and programmatic targets focus on diagnosis, treatment and prevention.
The impact targets are:
A mother to child transmission rate of less than 2%.
Less than 0.1% hepatitis B surface antigen (HBsAg) prevalence in children 5 years and under.
A combined annual mortality of 6 per 100,000 deaths or fewer attributable to hepatitis B or C
The programmatic targets are:
At least 90% coverage of 3 doses of HepB containing vaccines by 12 months of age.
At least 90% coverage of at-risk infants with targeted timely hepatitis B birth dose (HepB-BD).
At least 90% coverage of antenatal HBsAg screening.
At least 90% coverage with antivirals for eligible pregnant women.
100% of healthcare facilities with safe injections or 90% of healthcare injection devices procured to be safety-engineered
100% of blood donations to be screened
At least 90% of people living with chronic hepatitis B to be diagnosed.
At least 80% of people who are diagnosed with hepatitis B and eligible to be treated are treated.
We summarise England’s progress towards the WHO elimination targets for hepatitis B virus here and within the Hepatitis B in England Report. These metrics are updated annually. We will next update the data in November 2026.
England has consistently exceeded the WHO 90% coverage target for children receiving 3 doses of the hexavalent vaccine by their first birthday. The COVER annual report for 2024 to 2025 reported a slight increase in universal hexavalent vaccine coverage, with 91.3% of children being vaccinated by their first birthday compared to 91.2% in 2023 to 2024. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Coverage for universal hexavalent vaccine data for england has consistently exceeded the WHO 90% coverage target for children receiving 3 doses of the hexavalent vaccine by their first birthday. The COVER annual report for 2024 to 2025 reported a slight increase in universal hexavalent vaccine coverage, with 91.3% of children being vaccinated by their first birthday compared to 91.2% in 2023 to 2024. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Coverage of hepatitis B vaccination in the selective neonatal programme in England has increased over the past 6 years. The selective neonatal programme includes 5 hepatitis B vaccines (birth dose, monovalent dose at 4 weeks, and 3 hexavalent doses as part of the routine childhood immunisation schedule) by 12 months of age and a further monovalent dose at 12 months meaning that eligible infants should have all 6 doses by 24 months of age. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Selective neonatal programme data for coverage of hepatitis B vaccination in the selective neonatal programme in England has increased over the past 6 years. The selective neonatal programme includes 5 hepatitis B vaccines (birth dose, monovalent dose at 4 weeks, and 3 hexavalent doses as part of the routine childhood immunisation schedule) by 12 months of age and a further monovalent dose at 12 months meaning that eligible infants should have all 6 doses by 24 months of age. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Up to and including 31 December 2024
Year
Percentage vaccinated with 5 doses by 12 months old
Percentage vaccinated with 6 doses by 24 months old
31 Dec 2024
93.60
89.30
31 Dec 2023
91.00
88.00
31 Dec 2022
90.10
83.00
31 Dec 2021
88.50
80.80
31 Dec 2020
85.40
77.70
31 Dec 2019
83.90
72.80
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Source: Childhood vaccination coverage statistics, NHS Digital (co-authored with UKHSA).
Note 5: data prior to 2019 to 2020 is missing for some local authorities, particularly in London, and so is not presented. In July 2025 an additional hepatitis B hexavalent vaccine dose at 18 months of age was introduced to the universal schedule for babies reaching 12 months old on or after 1 July 2025; the monovalent vaccine dose at 12-months of age has therefore been removed from the selective schedule for these infants. The data presented here predates this change.
Coverage for timely hepatitis B birth dose vaccination
Whilst coverage of the hepatitis B birth dose vaccine within 24 hours of birth has remained high, and well over WHO targets (90% and above), there has been a small decline in recent years from 99.2% (1,834 out of 1,849) in 2020 to 2021 to 98.0% (1,786 out of 1,822) in 2023 to 2024. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Coverage for timely hepatitis B birth dose vaccination data for whilst coverage of the hepatitis B birth dose vaccine within 24 hours of birth has remained high, and well over WHO targets (90% and above), there has been a small decline in recent years from 99.2% (1,834 out of 1,849) in 2020 to 2021 to 98.0% (1,786 out of 1,822) in 2023 to 2024. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Up to and including 31 December 2023
Year
Proportion of infants with timely hepatitis birth dose
The estimated mother to child transmission rate has consistently been below the 2% WHO target, falling from 0.95% between April 2014 and March 2015 to 0.06% between April 2024 to March 2025. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Mother to child transmission rate data for the estimated mother to child transmission rate has consistently been below the 2% WHO target, falling from 0.95% between April 2014 and March 2015 to 0.06% between April 2024 to March 2025. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Antenatal screening uptake has consistently been above 99% between 2017 to 2024 exceeding the WHO target of 90%, ensuring that pregnant women living with hepatitis B are diagnosed and interventions are implemented to prevent transmission of hepatitis B to their children. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Maternal screening coverage data for antenatal screening uptake has consistently been above 99% between 2017 to 2024 exceeding the WHO target of 90%, ensuring that pregnant women living with hepatitis B are diagnosed and interventions are implemented to prevent transmission of hepatitis B to their children. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Up to and including 31 December 2023
Year
Hepatitis B screening coverage
WHO target
31 Dec 2023
99.80
90.00
31 Dec 2022
99.80
90.00
31 Dec 2021
99.80
90.00
31 Dec 2020
99.80
90.00
31 Dec 2019
99.80
90.00
31 Dec 2018
99.70
90.00
31 Dec 2017
99.50
90.00
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Source: IDPS programme standards reports and KPI indicator reports, NHSE.
Deaths from hepatitis B-related ESLD and/or HCC have remained below 0.36 per 100,000 population since 2005 using the upper bound estimate. In 2024, the estimated annual hepatitis B-related ESLD and/or HCC mortality rate was between 0.18 (lower bound) and 0.35 (upper bound) per 100,000 population, and this rate has remained stable with upper estimates between 0.15 and 0.36 since 2005. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Mortality rate per 100,000 population data for deaths from hepatitis B-related ESLD and/or HCC have remained below 0.36 per 100,000 population since 2005 using the upper bound estimate. In 2024, the estimated annual hepatitis B-related ESLD and/or HCC mortality rate was between 0.18 (lower bound) and 0.35 (upper bound) per 100,000 population, and this rate has remained stable with upper estimates between 0.15 and 0.36 since 2005. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Up to and including 31 December 2024
Year
Rate for hepatitis B-related ESLD and/or HCC
Amount
31 Dec 2024
0.18
4.00
31 Dec 2023
0.17
4.00
31 Dec 2022
0.15
4.00
31 Dec 2021
0.15
4.00
31 Dec 2020
0.17
4.00
31 Dec 2019
0.15
4.00
31 Dec 2018
0.15
4.00
31 Dec 2017
0.14
4.00
31 Dec 2016
0.14
4.00
31 Dec 2015
0.16
4.00
31 Dec 2014
0.12
4.00
31 Dec 2013
0.14
4.00
31 Dec 2012
0.17
4.00
31 Dec 2011
0.19
4.00
31 Dec 2010
0.18
4.00
31 Dec 2009
0.18
4.00
31 Dec 2008
0.17
4.00
31 Dec 2007
0.18
4.00
31 Dec 2006
0.17
4.00
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Note 15: lower bound represents deaths where ESLD and/or HCC and hepatitis B were reported in ONS death registrations (as year of death is now used this is not comparable with previously published estimates which used year the death was registered). Upper bound represents deaths where ESLD and/or HCC were reported in ONS death registrations and hepatitis B diagnoses were identified by linking between ONS deaths, HES hospital admissions data and laboratory diagnosis data to yield a maximum number of deaths attributable to hepatitis B related ESLD and/or HCC.
Note 16: excluding deaths of people aged under 16 and deaths registered in England where the deceased’s usual residence is outside England.
Note 17: defined by codes or text entries for ascites, bleeding oesophageal varices, hepato-renal syndrome, hepatic encephalopathy, or hepatic failure.
Between 2015 and 2024 an average of 332 acute hepatitis B diagnoses were reported annually to UKHSA (range from 175 to 457). Despite a continuous decline in the number of people with an acute hepatitis B infection in England since 2015, 277 individuals were reported in 2024 which indicates that reporting is returning to pre-pandemic levels. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Number of people diagnosed with acute hepatitis B data for between 2015 and 2024 an average of 332 acute hepatitis B diagnoses were reported annually to UKHSA (range from 175 to 457). Despite a continuous decline in the number of people with an acute hepatitis B infection in England since 2015, 277 individuals were reported in 2024 which indicates that reporting is returning to pre-pandemic levels. Figures are annual, but shown as at December of each year. For example, the figures for 2022 are shown as at "Dec 2022".
Up to and including 31 December 2024
Calendar year
Amount
31 Dec 2024
277.00
31 Dec 2023
303.00
31 Dec 2022
239.00
31 Dec 2021
175.00
31 Dec 2020
253.00
31 Dec 2019
333.00
31 Dec 2018
381.00
31 Dec 2017
445.00
31 Dec 2016
453.00
31 Dec 2015
457.00
31 Dec 2014
488.00
31 Dec 2013
414.00
31 Dec 2012
554.00
31 Dec 2011
589.00
31 Dec 2010
512.00
31 Dec 2009
597.00
31 Dec 2008
620.00
31 Dec 2003
695.00
31 Dec 2002
892.00
31 Dec 2001
608.00
31 Dec 2000
729.00
31 Dec 1999
752.00
31 Dec 1998
843.00
31 Dec 1997
652.00
31 Dec 1996
570.00
31 Dec 1995
612.00
31 Dec 1994
633.00
31 Dec 1993
629.00
31 Dec 1992
531.00
31 Dec 1991
572.00
31 Dec 1990
618.00
31 Dec 1989
583.00
31 Dec 1988
641.00
31 Dec 1987
784.00
31 Dec 1986
1,309.00
31 Dec 1985
1,761.00
31 Dec 1984
1,937.00
31 Dec 1983
1,274.00
31 Dec 1982
1,237.00
31 Dec 1981
1,197.00
31 Dec 1980
1,007.00
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Note 12: data from 2004 to 2008 is not available due to change in the reporting and surveillance system. Laboratory and clinical reporting systems were reinstated in 2008.
Note 13: UKHSA transitioned to a new case management system for notifiable diseases in 2024 which has impacted the identification of people with acute hepatitis B and likely resulted in underreporting.